Conditions · Alzheimer's disease & early-stage dementia
Alzheimer's disease & early-stage dementia — clinical trials in Canada
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30 open options
- TRIALPHASE2RECRUITING
Cannabidiol Medication Intervention Trial
CBD · Placebo — 5 sites
- TRIALNARECRUITING
The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia
Brain Health PRO · Brain Health PRO — 1 site
- TRIALNARECRUITING
Infrared Light for Memory Loss in Mild Cognitive Impairment (MCI)
Active tPBM device · Sham device — 1 site
- TRIALNARECRUITING
MRI Guided Closed-loop TMS-EEG
TMS — 1 site
- TRIALNARECRUITING
Evaluating the Feasibility of elleFA App Implementation
Implementation of elleFA smartphone application — 1 site
- TRIALNARECRUITING
ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing
In-laboratory polysomnography · Home Sleep Apnea Test — 1 site
- TRIALNARECRUITING
Aerobic Exercise for Older Adults at Increased Risk of Alzheimer's Disease and Related Dementias
Aerobic exercise · Stretch and Strength — 1 site
- TRIALNARECRUITING
Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment
Creatine monohydrate · Resistance training — 1 site
- TRIALNARECRUITING
Longitudinal Study Examining At-Home tDCS
Transcranial Direct Current Stimulation — 1 site
- TRIALPHASE3RECRUITING
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
KarXT · KarX-EC — 252 sites
- TRIALPHASE2RECRUITING
Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia
intermittent theta burst stimulation (iTBS) · Methylphenidate (MPH) — 1 site
- TRIALPHASE3RECRUITING
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
No Intervention — 229 sites
- TRIALPHASE3RECRUITING
A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
Trontinemab · Placebo — 7 sites
- TRIALPHASE2 / PHASE3RECRUITING
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
EXV-802 · Placebo · EXV-801 — 49 sites
- TRIALPHASE2RECRUITING
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
ML-007C-MA · Placebo — 55 sites
- TRIALPHASE3RECRUITING
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
KarXT — 431 sites
- TRIALPHASE2RECRUITING
Clinical Trial on Agitation in Alzheimer's Dementia
IGC-AD1-Active · IGC-AD1-Placebo — 31 sites
- TRIALNARECRUITING
dTMS for Subjective Cognitive Decline
Active Brainsway H7-Coil Deep TMS System · Sham Brainsway H7-Coil Deep TMS System · Cognitive Training — 1 site
- TRIALNARECRUITING
CONSTELLATIONS Living Lab: Improving the Care Transitions of Older Adults Living with Neurocognitive Disorders
CoMPAS+ MNCDs Program - Quality improvement program targeting the care transitions of patients living with a major neurocognitive disorder and their caregivers — 1 site
- TRIALNARECRUITING
Nature-based Virtual Reality Intervention for Depression in Alzheimer's Disease
nature-based virtual reality applications and videos · nature-based videos — 1 site
- TRIALNARECRUITING
SYNERGIC-2 Trial (SYNchronizing, Exercises and Remedies to GaIn Cognition@Home)
PMI@Home · Brain Health Pro — 8 sites
- TRIALPHASE2RECRUITING
Levetiracetam for Persons at Risk for Alzheimer's Disease
Levetiracetam (LEV) · Placebo — 2 sites
- TRIALPHASE3RECRUITING
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
KarXT · KarX-EC · Placebo — 119 sites
- TRIALPHASE3RECRUITING
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Xanomeline/Trospium Chloride Capsule · Xanomeline Enteric Capsule · Placebo — 162 sites
- TRIALNARECRUITING
Exercise as a Primer for Brain Stimulation in Vascular Cognitive Impairment No Dementia (VCIND)
tDCS · Exercise · Sham stimulation — 1 site
- TRIALNANOT_YET_RECRUITING
Exploring Feasibility, Acceptability and Impact of Using Neurofeedback with Persons with Mild Cognitive Impairment
Nonlinear dynamical neurofeedback (NLD) · Low energy neurofeedback system (LENS) · Brain Music — 1 site
- TRIALPHASE2 / PHASE3RECRUITING
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Remternetug (SC) · Matching Placebo (Remternetug) — 37 sites
- TRIALNARECRUITING
Understanding How Alzheimer's Disease Impacts the Therapeutic Response to Transcranial Direct Current Stimulation
tDCS and Cognitive Training — 1 site
- TRIALPHASE1RECRUITING
A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
ALN-APP · Placebo — 8 sites
- TRIALNARECRUITING
Preventing Falls in Older Adults With Cognitive Frailty
Balance and Strength Training Exercises with Health Coaching · Education Session — 1 site
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Not medical advice. Trial0 is a navigation service, not a medical provider. Nothing here is medical advice or a recommendation to pursue any treatment; eligibility matching is informational, based on published registry criteria, and only the trial site or treating clinician can determine actual eligibility. Decisions belong with the patient and their own doctors.