Conditions · Alzheimer's disease & early-stage dementia
Alzheimer's disease & early-stage dementia — clinical trials in France
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- TRIALPHASE3RECRUITING
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
KarXT — 429 sites
- TRIALPHASE3RECRUITING
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Acoramidis · Placebo oral tablet — 104 sites
- TRIALNARECRUITING
EfFect of Ablation of Persistent AtriaL Fibrillation on COgNitive Function in Individuals With Mild Cognitive Impairment
Atrial fibrillation ablation + antiarrhythmic drugs · Antiarrhythmic drug — 8 sites
- TRIALNARECRUITING
Identification of Diagnosis Biomarkers in the Tears of Alzheimer's Disease Patients: The COG-EYE Pilot Study
Basal tear collection for the analysis of metabo-lipidomic profiles and concentrations of protein biomarkers (Tau, phosphorylated Tau, Aβ 1-40, and Aβ 1-42) · Collection of a blood sample (5 mL) for blood biomarkers analysis — 1 site
- TRIALPHASE2ENROLLING_BY_INVITATION
An Open-Label Study of ML-007C-MA in Adults With Alzheimer's Disease Psychosis
ML-007C-MA — 8 sites
- TRIALNARECRUITING
Biomarkers of Sleep-wake Cycle in Prodromal Alzheimer's Disease: Role in Cognitive Decline?
Polysomnography · Neuropsychological assessment · Questionnaires on sleep and behavioural problems — 3 sites
- TRIALNARECRUITING
Predictive Factors and Autonomy Level Change
The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6 — 2 sites
- TRIALPHASE2RECRUITING
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
ML-007C-MA · Placebo — 55 sites
- TRIALNARECRUITING
Predictive Factors of Autonomy Loss in Real-life Cohort
no intervention — 5 sites
- TRIALPHASE2RECRUITING
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
VHB937 · VHB937 · Placebo — 74 sites
- TRIALPHASE3RECRUITING
Effect of CAFfeine on Cognition in Alzheimer's Disease
Caffeine · Placebo — 17 sites
- TRIALPHASE3ENROLLING_BY_INVITATION
ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study
ACP-204 — 76 sites
- TRIALNARECRUITING
MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY
TEP/IRM — 2 sites
- TRIALPHASE3RECRUITING
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
KarXT · KarX-EC · Placebo — 119 sites
- TRIALPHASE2RECRUITING
Biomarkers of the Locus Coeruleus Nucleus: Links With Early Tau Pathology, Cognition and Alzheimer's Disease Risk
a positon emission tomography (PET) exam · MRI Contrast · oculometry assessment — 1 site
- TRIALPHASE3RECRUITING
Donepezil Versus Non-drug Treatment in Alzheimer's Disease.
Donepezil — 1 site
- TRIALPHASE3RECRUITING
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
KarXT · Placebo — 296 sites
- TRIALNANOT_YET_RECRUITING
Early-phase Telecare Programs for Minor Stroke
Psychoeducation · Computerised Cognitive Stimulation · Usual Care — 3 sites
- TRIALNARECRUITING
Efficacy of RGn600 in Patients With Mild-to-moderate Alzheimer's Disease
RGn600 · RGn600 Sham — 7 sites
- TRIALNANOT_YET_RECRUITING
MUSic Listening Impact on QUality of Life, Brain and Burnout of ALzheimer' Patients Informal Caregivers
listening intervention · Neuropsychology assessment · brain imaging examination — 1 site
- TRIALPHASE3NOT_YET_RECRUITING
Masitinib in Patients With Mild Alzheimer's Disease
Placebo · Masitinib (4.5) · Standard of care — 9 sites
- TRIALNANOT_YET_RECRUITING
Idiopathic Parkinson's Disease: Interest of an Early Group-Based Cognitive Rehabilitation Program (LIFECOG-PD)
cognitive rehabilitation program — 1 site
- TRIALNARECRUITING
MIMA Pilot Study: MIcrostructure of the Medial Temporal Lobe in Early Alzheimer's Disease
high-resolution diffusion MRI — 1 site
- TRIALPHASE2 / PHASE3RECRUITING
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Remternetug · Matching Placebo (Remternetug) — 37 sites
- TRIALPHASE2 / PHASE3RECRUITING
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Remternetug (SC) · Matching Placebo (Remternetug) — 37 sites
- TRIALNARECRUITING
Five Lives MED to Improve Cognitive Function in Mild Cognitive Impairment
Five Lives MED — 7 sites
- TRIALNARECRUITING
Sleep Impairment in Subjects at Risk of Developing Alzheimer's Disease
Polysomnography · Neuropsychological assessment · Questionnaires on sleep and behavioural problems — 1 site
- TRIALNANOT_YET_RECRUITING
Physical Exercise to Prevent Mild-cognitive Impairment in Patients With Kidney Disfunctions
Exercise · Control (Standard treatment) — 6 sites
- TRIALNARECRUITING
Effects of Musical Intervention by a Therapist (IMT) on Falling Asleep and Behavioral Regulation in a Secure Care Unit (SCU)
Test musicale intervention · Controle: audio book — 1 site
- TRIALNARECRUITING
Validation of a Remediation Method for Memory Impairments Through Motor Encoding in Patients With Alzheimer's Disease
Control condition · Motor mental imagery · Action execution — 3 sites
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