Conditions · Alzheimer's disease & early-stage dementia
Alzheimer's disease & early-stage dementia — clinical trials in Spain
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- TRIALNANOT_YET_RECRUITING
Intervention to Reduce Unwanted Loneliness in Family Caregivers of People With Alzheimer
Multimodal intervention to Reduce Unwanted Loneliness in Family Caregivers of People With Alzheimer — 1 site
- TRIALPHASE3NOT_YET_RECRUITING
Masitinib in Patients With Mild Alzheimer's Disease
Placebo · Masitinib (4.5) · Standard of care — 9 sites
- TRIALNARECRUITING
Brief Problem-solving Intervention in Different Formats for the Prevention of Suicide in Adults Over 50
Problem-solving-based psychological intervention — 1 site
- TRIALNARECRUITING
Effects of a Computerised Cognitive Stimulation Versus Stimulating Leisure Activities
Cognitive stimulation · Stimulating leisure activities — 1 site
- TRIALPHASE3RECRUITING
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
KarXT · KarX-EC — 252 sites
- TRIALPHASE3RECRUITING
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
No Intervention — 229 sites
- TRIALNARECRUITING
Analyzing the Benefits of Using SYMPTOMS-JIT for in Vivo Exposure in Anxiety Disorders
Cognitive behavioral therapy with in vivo exposure · Cognitive behavorial therapy with in vivo exposure plus SYMPTOMS-JIT — 1 site
- TRIALPHASE2 / PHASE3RECRUITING
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
EXV-802 · Placebo · EXV-801 — 49 sites
- TRIALPHASE3RECRUITING
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
KarXT — 431 sites
- TRIALNARECRUITING
Computerized Cognitive Training in Healthy Older Adults and Mild Cognitive Impairment
Computerized Cognitive Training · Active Control Computerized Activities — 2 sites
- TRIALNAENROLLING_BY_INVITATION
Validation Study of a New Digital Diagnostic and Treatment Test Based on Interactive Video Games for Alzheimer's Disease
Bgaze Therapy · Bgaze Attention Task — 1 site
- TRIALPHASE3RECRUITING
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
KarXT · KarX-EC · Placebo — 127 sites
- TRIALPHASE2RECRUITING
A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Mivelsiran · Placebo — 3 sites
- TRIALNANOT_YET_RECRUITING
Acoustic Stimulation During Sleep: Effects on Memory and p-tau217 in MCI
Plase-Locked Acoustic Stimulation during slow-wave sleep · Phase-locked acoustic stimulation-Sham condition — 1 site
- TRIALPHASE3ENROLLING_BY_INVITATION
ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study
ACP-204 — 76 sites
- TRIALNANOT_YET_RECRUITING
Benefits of Strength Training in Informal Caregivers of Patients With Alzheimer's Disease
Progressive Muscle Relaxation · Functional Strength Training — 1 site
- TRIALNARECRUITING
Personalized Brain Health Service and Dementia Prevention
Multimodal Lifestyle Intervention · Lifestyle Recommendations and Counseling — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
Placebo (Study Part 1a) · ACI-24.060 at Dose A in Study Part 1a · ACI-24.060 at Dose B in Study Part 1a — 26 sites
- TRIALPHASE3RECRUITING
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
KarXT · KarX-EC · Placebo — 119 sites
- TRIALPHASE3RECRUITING
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Xanomeline/Trospium Chloride Capsule · Xanomeline Enteric Capsule · Placebo — 162 sites
- TRIALPHASE2 / PHASE3RECRUITING
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Remternetug (SC) · Matching Placebo (Remternetug) — 37 sites
- TRIALNARECRUITING
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
Video-Implemented Script Training for Aphasia (VISTA) · Lexical Retrieval Training (LRT) — 3 sites
- TRIALNAENROLLING_BY_INVITATION
Obstructive Sleep Apnea and Biomarkers of Alzheimer's Disease
Continuous positive airway pressure — 2 sites
- TRIALPHASE3RECRUITING
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
KarXT · Placebo — 296 sites
- TRIALPHASE3RECRUITING
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Acoramidis · Placebo oral tablet — 104 sites
- TRIALPHASE1RECRUITING
A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease
ALN-5288 · Placebo — 13 sites
- TRIALNANOT_YET_RECRUITING
Neuroprotective Effects of Oleanolic Acid and Erythrodiol in Prodromal Alzheimer's Disease
Oleanolic acid-enriched olive oil · Pomace olive oil · Commercial olive oil 0.4 degrees — 1 site
- TRIALNARECRUITING
Effectiveness of an ACT-Based Cognitive Intervention on Quality of Life and Cognitive Function in Elderly Residents With MCI
Acceptance and Commitment Therapy (ACT) · standard care — 1 site
- TRIALPHASE3NOT_YET_RECRUITING
Tributyrin Treatment in Mild Alzheimer Disease: Assessment of Butyrate Effects Via the Gut-Brain
tributyrin · Placebo — 1 site
- TRIALNANOT_YET_RECRUITING
Effects of Resistance and Dual-Task Training on Physical, Oculomotor, and Executive Functions in Older Adults With MCI
Anaerobic therapeutic exercises (resistance exercise) · Anaerobic therapeutic exercises (resistance exercise) plus Dual Task — 2 sites
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