Glioblastoma — drug options
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30 open options
- TRIALEARLY_PHASE1NOT_YET_RECRUITING
A Study of NST-628 in Recurrent Grade 4 Glioma
NST-628 — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma
Intra-arterial Cetuximab · Intra-arterial Mannitol — 1 site
- TRIALEARLY_PHASE1RECRUITING
Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures
Panitumumab-IRDye800 — 1 site
- TRIALPHASE2RECRUITING
ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas
ACT001 — 20 sites
- TRIALPHASE1 / PHASE2RECRUITING
Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma
Pembrolizumab · Stereotactic Radiation Therapy · Surgical Resection — 1 site
- EXPANDED ACCESSAVAILABLE
BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast
DNG64-CAR-V — 1 site
- TRIALPHASE3RECRUITING
Advanced Imaging Techniques for Evaluating the Tumor Immune Microenvironment in Glioblastoma Patients
Biospecimen Collection · Chemical Exchange Saturation Transfer Magnetic Resonance Imaging · Diffusion-Relaxation Correlation Spectrum Imaging — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
IA Carboplatin + Radiotherapy in Relapsing GBM
IA Carbo+ Radiation — 1 site
- TRIALEARLY_PHASE1RECRUITING
Window of Opportunity Study of DSP-0390 in Gliomas
DSP-0390 — 1 site
- TRIALNARECRUITING
Allogeneic γδT Cells in Glioblastoma
Allogeneic γδ T (ABOUT) cells — 3 sites
- TRIALPHASE2NOT_YET_RECRUITING
Survivin-Targeted Dendritic Cell (DC) Cell Injection for Newly Diagnosed Glioblastoma
Survivin-targeted DC Cell Injection
- TRIALEARLY_PHASE1RECRUITING
18F-Fluciclovine PET-MRI in High-grade Glioma
18F-Fluciclovine PET-MRI — 1 site
- TRIALEARLY_PHASE1RECRUITING
Imaging Acetadote Metabolism in Glioblastoma
Acetadote — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors
LAM561 — 3 sites
- TRIALEARLY_PHASE1NOT_YET_RECRUITING
Oral Gallium Maltolate for Recurrent Glioblastoma
Gallium Maltolate · Surgical Intervention — 1 site
- TRIALPHASE1NOT_YET_RECRUITING
Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid Tumor
Gallium maltolate
- TRIALPHASE1RECRUITING
Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma
Dual-target CAR-NK cells · Cyclophosphamide · Intracranial catheter/reservoir for locoregional delivery — 1 site
- TRIALPHASE2RECRUITING
Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer
Trastuzumab deruxtecan — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery
Near-Infrared Fluorescence Imaging · Panitumumab · Panitumumab-IRDye800 — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma
TGX-007 · Valaciclovir — 2 sites
- TRIALPHASE1RECRUITING
A Clinical Trial on Combined (Neo-)Adjuvant Intravenous Plus Intracranial Administration of Ipilimumab and Nivolumab in Recurrent Glioblastoma
Neo-adjuvant nivolumab and ipililumab IV + adjuvant nivolumab and ipililumab IV · Neurosurgery and intracavitary injection nivolumab and ipililumab · Adjuvant nivolumab IV + nivolumab and ipililumab intracavitary — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM
ADV/HSV-tk (gene therapy) — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
LMP744 · Conventional Surgery or Biopsy — 1 site
- TRIALPHASE2RECRUITING
Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA
Intra-arterial Cetuximab · Intra-arterial Mannitol · Hypofractionated re-irradiation — 1 site
- TRIALPHASE1NOT_YET_RECRUITING
CM93 Treatment in Subjects With Epidermal Growth Factor Receptor (EGFR)-Modified Recurrent Glioblastoma (rGBM)
CM93
- TRIALPHASE1NOT_YET_RECRUITING
A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma.
CBX-663 — 1 site
- TRIALPHASE1RECRUITING
D2C7-IT + 2141-V11 Combination Post-resection in rGBM
D2C7-IT · 2141 V11 — 1 site
- TRIALPHASE1ENROLLING_BY_INVITATION
Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma
Nivolumab · Azacitidine (AZA) · lumbar puncture — 1 site
- TRIALPHASE1NOT_YET_RECRUITING
FPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With Glioblastoma
Biospecimen Collection · Computed Tomography · Dexamethasone — 1 site
- TRIALPHASE2RECRUITING
Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature
ACT001 — 1 site
Live from ClinicalTrials.gov, refreshed at most hourly · registry query ↗
Not medical advice. Trial0 is a navigation service, not a medical provider. Nothing here is medical advice or a recommendation to pursue any treatment; eligibility matching is informational, based on published registry criteria, and only the trial site or treating clinician can determine actual eligibility. Decisions belong with the patient and their own doctors.