Pancreatic cancer — clinical trials in Italy

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TRIALNANOT_YET_RECRUITING
Personalised Nutritional Care in Older Patients With Pancreatic Ductal Adenocarcinoma
Experimental: Personalised nutritional care delivered by a trained dietitian — 5 sites
TRIALPHASE1RECRUITING
A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
ASP2138 · Pembrolizumab · Oxaliplatin — 46 sites
TRIALPHASE2RECRUITING
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Belzutifan — 84 sites
TRIALPHASE1RECRUITING
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
Sofe-M · bevacizumab · carboplatin — 24 sites
TRIALPHASE1RECRUITING
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
INCB161734 · Cetuximab · Retifanlimab — 34 sites
TRIALPHASE1RECRUITING
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
AMG 410 · Pembrolizumab · Panitumumab — 39 sites
TRIALPHASE2 / PHASE3RECRUITING
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
ponsegromab · placebo — 223 sites
TRIALPHASE2RECRUITING
Conversion Surgery Vs. Palliative Care in Pancreatic Cancer Oligometastatic to the Liver
Surgical resection of both the primary tumor and liver metastases — 1 site
TRIALPHASE3RECRUITING
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
Paltusotine · Placebo — 73 sites
TRIALNARECRUITING
Prehabilitation in Pancreatic Surgery
Multimodal Prehabilitation — 1 site
TRIALPHASE2 / PHASE3RECRUITING
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Zanzalintinib · Everolimus — 126 sites
TRIALNARECRUITING
Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE)
Stereotactic body radiotherapy · Palliative RT — 13 sites
TRIALPHASE1 / PHASE2RECRUITING
Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma
RR001 — 1 site
TRIALPHASE1 / PHASE2RECRUITING
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
Risvutatug Rezetecan · Drug 1 · Drug 2 — 85 sites
TRIALPHASE2RECRUITING
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
BAY2927088 — 54 sites
TRIALNARECRUITING
Biophotonic Nanoparticle-enabled Laser Blood Test for Early Detection of Pancreatic Cancer
Diagnostic procedures — 1 site
TRIALNARECRUITING
Electrochemotherapy (ECT) in Patients With Primary Visceral Tumors and/or Secondary Visceral Localizations, of Any Histotype
percutaneous, laparoscopic or laparotomy lesion electrochemotherapy — 1 site
TRIALNARECRUITING
Alpha Radiation Emitters for the Treatment of Pancreatic Cancer for the Treatment of Locally Advanced Pancreatic Cancer
DaRT seeds insertion — 1 site
TRIALPHASE1RECRUITING
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
Darlifarnib · Cabozantinib · Adagrasib — 38 sites
TRIALPHASE1RECRUITING
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
LY3962673 · Cetuximab · Gemcitabine — 52 sites
TRIALPHASE4RECRUITING
Efficacy of PERT for PEI in Unresectable Pancreatic Cancer.
creon 35.000 Ph.U (R) · Best Standarard of Care — 4 sites
TRIALPHASE2 / PHASE3RECRUITING
Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer
SBP-101 · Nab-paclitaxel · Gemcitabine — 93 sites
TRIALPHASE1 / PHASE2RECRUITING
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
Sacituzumab tirumotecan · Fluorouracil (5-FU) · Leucovorin (LV) or levoleucovorin — 55 sites
TRIALNARECRUITING
Gut Microbiota Analysis in Patients Undergoing Duodencephalopancreasectomy for Pancreatic Cancer
Microbiota analysis — 1 site
TRIALNANOT_YET_RECRUITING
PAN-CLO-BU (PANcreas-CLOstridium-BUtyricum)
Clostridium butyricum CBM588 Strain · Placebo — 1 site
TRIALPHASE2RECRUITING
A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
BMS-986504 · Daraxonrasib · Nivolumab + Relatlimab FDC — 58 sites
TRIALPHASE3RECRUITING
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
INCB161734 · Placebo · Investigator's choice of chemotherapy — 228 sites
TRIALPHASE2RECRUITING
[68Ga]BED003 PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
[68Ga]BED003 — 6 sites
TRIALPHASE3RECRUITING
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
daraxonrasib — 78 sites
TRIALNARECRUITING
Para-aortic Lymphnodes Removal During Upfront Pancreaticoduodenectomy
removal of para-aortic lymphnodes (PALN) — 1 site

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