Trial0

Clinical trial · NCT06914349

Antecolic Versus Retrocolic Gastrojejunostomy During Whipple's Procedure

Recruiting

Sponsor: University of Thessaly

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Summary

Aim: This randomized clinical study aims to compare occurrence of DGE in patients undergoing either antecolic or retrocolic gastrojejunostomy following pancreaticoduodenectomy. Methods: Participants of this study will be patients undergoing pylorus preserving pancreaticoduodenectomy at the Surgical Department of the University Hospital of Larissa. Patients will be randomized to undergo either an antecolic or a retrocolic gastrojejunostomy and the occurrence of DGE will then be compared between the two groups. Individuals younger than 18 or older than 75 years old, as well as patients who do not consent to participate in this trial, will be excluded. Expected results: Based on available literature, antecolic gastrojejunostomy may be related with a lower incidence of DGE, without a statistically significant difference between the two methods. We aim to show if one of the two methods of gastrointestinal reconstruction (antecolic versus retrocolic) affects DGE.

Interventions

  • Antecolic gastrojejunostomy · PROCEDURE

    Gastrojejunostomy in front of the transverse colon

  • Retrocolic gastrojejunostomy · PROCEDURE

    Gastrojejunostomy through the transverse mesocolon

Published eligibility criteria

Verbatim from the registry. Only the site can decide how these apply to a specific patient.

Inclusion Criteria:

* Age over 18 years old
* Elective pancreaticoduodenectomy
* Signed consent form

Exclusion Criteria:

* Age under 18 years old
* Patients who are participants in other trials that may affect the results of this study
* Patients who do not consent to participate in the study

Sites (1)

  • University of Thessaly, Larissa, Greece · Recruiting

Not medical advice. Trial0 is a navigation service, not a medical provider. Nothing here is medical advice or a recommendation to pursue any treatment; eligibility matching is informational, based on published registry criteria, and only the trial site or treating clinician can determine actual eligibility. Decisions belong with the patient and their own doctors. Registry data refreshed at most hourly; last update posted 2025-06-06.

Antecolic Versus Retrocolic Gastrojejunostomy During Whipple's Procedure (NCT06914349) — Trial0