Conditions · Alzheimer's disease & early-stage dementia
Alzheimer's disease & early-stage dementia — clinical trials in United States
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30 open options
- TRIALPHASE1 / PHASE2RECRUITING
Large-coil Parietal Repetitive Transcranial Magnetic Stimulation (rTMS) for Alzheimer Disease (AD)
TMS · Transcranial Magnetic Stimulation Sham — 1 site
- TRIALNARECRUITING
Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain
Just-In-Time Adaptive Interventions (JITAIs) · Wysa for Chronic Pain — 1 site
- TRIALEARLY_PHASE1RECRUITING
LpD3.5 Intervention Study in Older Adults- LISA-I Trial
LpD3.5 · Placebo — 1 site
- TRIALNANOT_YET_RECRUITING
Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 2
Project 2, Phase 2: Intelligent Adaptive System — 3 sites
- TRIALPHASE1 / PHASE2RECRUITING
Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease
IL-2 (Aldesleukin) · Semaglutide Plus IL-2 · Placebo — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Nicotinic Acid for the Treatment of Alzheimer's Disease
Placebo Comparator · Extended Release Niacin — 1 site
- TRIALNARECRUITING
Designing Care Management for Hospice Transitions for Persons Living With Advanced Dementia
Dementia Care Management Checklist for Hospice Transitions — 1 site
- TRIALPHASE1 / PHASE2NOT_YET_RECRUITING
A Nutritional and Pharmacological Intervention for Body, Brain, and Longevity Effects (NIBBLE)
FMD1 (LNT22-017-1) · Rapamycin · Placebo — 1 site
- TRIALNARECRUITING
Michigan Healthy Mom (MI-MOM) Pregnancy Improvement Web Application Trial
MI MOM App — 8 sites
- TRIALNAENROLLING_BY_INVITATION
Comparative Study of High Performance Low-Cost Optical Coherence Tomography (Stage 1B, 2 and 3)
retinal imaging with low-cost OCT-a/LCI device — 1 site
- TRIALPHASE3RECRUITING
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
Donanemab · Placebo — 59 sites
- TRIALPHASE3RECRUITING
Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease
[F-18]Flornaptitril — 1 site
- TRIALPHASE4RECRUITING
Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis
Acoramidis (AG10) oral tablet — 1 site
- TRIALNARECRUITING
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Metronome — 1 site
- TRIALPHASE2RECRUITING
Human Mesenchymal Stem Cells & Monoclonal Antibodies in the Treatment for Mild Cognitive Impairment or Early Alzheimer's Disease.
human Mesenchymal Stem Cells — 1 site
- TRIALNARECRUITING
Transcranial Magnetic Stimulation for MCI
Accelerated iTBS · Sham Comparator — 1 site
- TRIALPHASE1NOT_YET_RECRUITING
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
PROSOMNIA Sleep Therapy™ (PSTx) · Anesthesia-Induced Sleep Therapy · Diprivan (propofol), Astra-Zeneca — 1 site
- TRIALPHASE4NOT_YET_RECRUITING
Light and Sleep Fragmentation
Light therapy — 1 site
- TRIALPHASE1RECRUITING
TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
Time-restricted eating — 1 site
- TRIALNARECRUITING
Personalized Obstructive Sleep Apnea Treatment and Effects on Alzheimer's Disease Biomarkers and Cognition Among Blacks
Standard of Care · Personalized OSA Treatment — 1 site
- TRIALPHASE2RECRUITING
Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)
GENUS · Tactile GENUS — 1 site
- TRIALPHASE2RECRUITING
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial
Cognitive Training — 4 sites
- TRIALPHASE1NOT_YET_RECRUITING
DUVAX: A Phase 1 Alzheimer's Vaccine Study Targeting Amyloid-Beta and Tau
DUVAX 200 µg · DUVAX 400 µg · Placebo (Adjuvant only) — 1 site
- TRIALNARECRUITING
Pulsed Electromagnetic Field Treatment With Dementia Patients
ECHS AD Device — 1 site
- TRIALPHASE2RECRUITING
Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X)
CORT108297 · Placebo — 1 site
- TRIALPHASE1 / PHASE2RECRUITING
Snacks and Brain Health
Pecan snack · Pretzel snack — 1 site
- TRIALNARECRUITING
Early-Stage Partner in Care Living Alone Plus
Psychoeducational skills training intervention — 1 site
- TRIALNARECRUITING
Music for Pain and Dementia
Drumming session · Music-listening session — 1 site
- TRIALNAENROLLING_BY_INVITATION
TMS Pilot in Early AD II
Intermittent theta burst stimulation active coil · Sham coil — 1 site
- TRIALNARECRUITING
Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)"
Physical activity · Successful Aging — 1 site
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